Prognosis of liver Cancer Resection-LiverRP

EpiSante Biomedical | LiverRP-Prognosis of liver Cancer Resection | DNA methylation analysis | cancer management

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LiverRP-Prognosis of liver Cancer Resection

Liver cancer resection is the first choice for patients in the early stages of liver cancer and is one of the few methods that can cure liver cancer. However, the long-term survival rate following liver cancer resection is still not satisfactory, due to its high recurrence rate of up to 70% within five years. LiverRP can assist doctors in formulating postoperative treatment strategies, such as closely monitoring patients with a poor prognosis or administering preventive treatment, to increase survival rates.

Our Advantages

LiverRP is the world's first product that uses methylation markers as a prognostic tool for liver cancer resection.

World-leading

LiverRP is the world's first product that uses methylation markers as a prognostic tool for liver cancer resection.
Compared to current biochemical markers and clinical pathological evaluations, LiverRP can serve as a more precise postoperative assessment tool.

Precise

Compared to current biochemical markers and clinical pathological evaluations, LiverRP can serve as a more precise postoperative assessment tool.
LiverRP是用手術切除後的組織做檢測,無須額外採檢

Convenient

LiverRP uses tissue samples removed during surgery for testing, eliminating the need for additional sampling.
LiverRP uses qMSP (quantitative methylation specific PCR) technology, with an exclusive patented gene panel, to improve precision and testing throughput.

Innovative

LiverRP uses qMSP technology, with an exclusive patented gene panel, to improve precision and testing throughput.

Who needs the testing?

Patients treated with liver resection

Clinical Performance of LiverRP

Clinical Performance of LiverRP - AUC

LiverRP臨床效能 - AUC
AUC (Area Under Curve) is the area under the ROC curve, representing the ability to predict cancer.
AUC=1 means both sensitivity and specificity are 100%. AUC = 0.5 represents no discrimination; AUC between 0.6 and 0.7 is acceptable discrimination; AUC between 0.7 and 0.8 has excellent discrimination; AUC between 0.9 and 1 represents excellent discrimination.

Clinical Performance of LiverRP- Sensitivity

LiverRP臨床效能 - 靈敏度
Sensitivity, also known as the true positive rate, refers to the proportion of actual early recurrence of liver cancer samples that are detected and diagnosed as early recurrence of liver cancer.

Clinical Performance of LiverRP- Specificity

LiverRP臨床效能 - 特異度
Specificity, also known as the true negative rate, refers to the proportion of actual non-early recurrence of liver cancer samples that are judged to be non-early recurrence of liver cancer.

Clinical Performance of LiverRP-prediction of 5-year survival

LiverRP臨床效能 – 五年存活率預測
According to the results of the LiverRP test, the five-year survival rate for liver cancer patients judged to be at low risk is 91.3%, while the fiveyear survival rate for highrisk patients is 43.6%. The results show that LiverRP can effectively assess high-risk patients after surgery and those with poor prognosis.
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